LONP2

Across TCGA cell cohorts, LONP2 mutation is significantly associated with the RNA expression of many other genes, with 47 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible LONP2-associated genes across cancer lineages are KRTAP19-5, MMP27, and IFNW1. Each is linked with LONP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LONP2-to-partner and partner-to-LONP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP19-5 grouped by LONP2-low versus LONP2-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LONP2→partner) and Y-score (partner→LONP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	KRTAP19-5 →	+0.142	+4.129	<.001	.007	3	2
SOFT_TISSUE	MMP27 →	+0.098	+4.635	<.001	.003	3	1
KIDNEY	IFNW1 →	+0.014	+4.121	<.001	.006	3	1
KIDNEY	PRSS45P →	+0.033	+4.121	<.001	.006	3	1
KIDNEY	CXorf49B →	+0.082	+4.121	<.001	.006	3	1
KIDNEY	CXorf49 →	+0.082	+4.121	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

KRTAP19-5 by LONP2 expression — STOMACH

Explore this box plot interactively →