Across TCGA cell cohorts, LONP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,648 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LONP1-associated GO terms across cancer lineages are Energy coupled proton transmembrane transport, against electrochemical gradient, Electron transport coupled proton transport, and Cytoplasm protein quality control by the ubiquitin-proteasome system. Each is linked with LONP1 in more than 17 cancer types. Because this analysis shows association rather than direction, both LONP1-to-partner and partner-to-LONP1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LONP1→partner) and Y-score (partner→LONP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.121	+1.251	<.001	<.001	3	18
BONE	Electron transport coupled proton transport →	+0.121	+1.251	<.001	<.001	3	18
BONE	Cytoplasm protein quality control by the ubiquitin-proteasome system →	+0.241	+1.409	<.001	<.001	3	14
BONE	Cytoplasm protein quality control →	+0.199	+1.388	<.001	<.001	3	14
BONE	Mitochondrial tRNA wobble uridine modification →	+0.151	+0.813	.001	.002	3	12
URINARY_TRACT	Regulation of cellular response to osmotic stress →	+0.155	+0.998	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,648 associations by consensus.

Exploration

LONP1 survival (RNA) · tumor vs normal (RNA) · all LONP1 data types