LNX2

Across TCGA cell cohorts, LNX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,060 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LNX2-associated GO terms across cancer lineages are Positive regulation of cytoplasmic mRNA processing body assembly, Nuclear-transcribed mRNA poly(A) tail shortening, and Negative regulation of hematopoietic stem cell differentiation. Each is linked with LNX2 in more than 15 cancer types. Because this analysis shows association rather than direction, both LNX2-to-partner and partner-to-LNX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cytoplasmic mRNA processing body assembly grouped by LNX2-low versus LNX2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LNX2→partner) and Y-score (partner→LNX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of cytoplasmic mRNA processing body assembly →	+0.122	+0.872	<.001	<.001	3	16
OVARY	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.110	+0.601	<.001	.001	3	12
OESOPHAGUS	Negative regulation of hematopoietic stem cell differentiation →	+0.167	+0.863	.001	<.001	3	12
BLOOD_Myeloma	Copper ion export →	-0.188	-0.730	.001	.002	3	12
LUNG_SCLC	Regulation of cytoplasmic mRNA processing body assembly →	+0.111	+0.834	<.001	<.001	3	12
LUNG_SCLC	Establishment of apical/basal cell polarity →	-0.177	-0.972	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,060 associations by consensus.

Positive regulation of cytoplasmic mRNA processing body assembly by LNX2 expression — LUNG_SCLC

Explore this box plot interactively →