LNPEP

Across TCGA patient cohorts, LNPEP RNA expression is significantly associated with the protein abundance of many other proteins, with 12,819 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LNPEP-associated proteins across cancer lineages are JADE2, RPS8, and LYSMD2. Each is linked with LNPEP in more than 4 cancer types. Because this analysis shows association rather than direction, both LNPEP-to-partner and partner-to-LNPEP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LNPEP versus JADE2 in GBM, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LNPEP→partner) and Y-score (partner→LNPEP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	JADE2 →	+0.360	+0.318	<.001	.002	3	5
BRCA	RPS8 →	-0.283	-0.622	<.001	<.001	3	4
PDAC	LYSMD2 →	+0.332	+0.206	.004	.003	3	4
LSCC	AP3S1 →	+0.200	+0.375	.001	.002	3	4
BRCA	MAPK9 →	+0.275	+0.566	<.001	<.001	3	4
HNSC	PIK3R1 →	+0.247	+0.438	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,819 associations by consensus.

LNPEP vs JADE2 — GBM

Explore this scatter interactively →