Across TCGA cell cohorts, LNP1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible LNP1-associated genes across cancer lineages are SPATA48 and OR6S1. Each is linked with LNP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LNP1-to-partner and partner-to-LNP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LNP1→partner) and Y-score (partner→LNP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	SPATA48 →	+0.006	+5.285	<.001	.003	3	1
STOMACH	OR6S1 →	+0.063	+5.285	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

LNP1 survival (RNA) · tumor vs normal (RNA) · all LNP1 data types