Across TCGA pan-cancer cohorts, LNCPRESS1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LNCPRESS1’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where LNCPRESS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LNCPRESS1 is over-expressed in tumor, although a few such as LIHC show the opposite, repressed pattern.
KICH and LIHC are the cancer types where LNCPRESS1 tumor–normal differential expression is most reproducible.