LMX1B

Across TCGA patient cohorts, LMX1B protein abundance is significantly associated with the RNA expression of many other genes, with 5,576 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LMX1B-associated genes across cancer lineages are SEC14L2, SPECC1L, and PPIL2. Each is linked with LMX1B in more than 1 cancer types. Because this analysis shows association rather than direction, both LMX1B-to-partner and partner-to-LMX1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LMX1B versus SEC14L2 in BRCA, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMX1B→partner) and Y-score (partner→LMX1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEC14L2 →	+1.050	+0.623	.005	.002	3	1
BRCA	SPECC1L →	+0.470	+0.741	.003	.003	3	1
BRCA	PPIL2 →	+0.564	+0.612	<.001	.002	3	1
BRCA	TOP3B →	+0.065	+0.716	.007	<.001	3	1
BRCA	CARD10 →	+0.890	+0.588	<.001	<.001	3	1
BRCA	GRK3 →	+0.703	+0.711	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,576 associations by consensus.

LMX1B vs SEC14L2 — BRCA

Explore this scatter interactively →