LMX1B

Across TCGA patient cohorts, LMX1B mutation is significantly associated with the RNA expression of many other genes, with 1,098 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LMX1B-associated genes across cancer lineages are RBAK-RBAKDN, OR5D2P, and RNU4-67P. Each is linked with LMX1B in more than 2 cancer types. Because this analysis shows association rather than direction, both LMX1B-to-partner and partner-to-LMX1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBAK-RBAKDN grouped by LMX1B-low versus LMX1B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMX1B→partner) and Y-score (partner→LMX1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RBAK-RBAKDN →	+0.095	+2.253	.001	.003	3	3
UCEC	OR5D2P →	+0.052	+3.707	.004	.002	3	3
BRCA	RNU4-67P →	+0.501	+7.731	<.001	.009	3	3
COAD	PARP2 →	+0.440	+3.352	.003	.005	3	3
COAD	SKA2 →	+0.555	+3.183	.006	.009	3	3
LIHC	MIR6877 →	+0.400	+4.878	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,098 associations by consensus.

RBAK-RBAKDN by LMX1B expression — UCEC

Explore this box plot interactively →