LMX1A-AS1

Across TCGA pan-cancer cohorts, LMX1A-AS1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated LMX1A-AS1 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher LMX1A-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LMX1A-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and LGG show a favorable association.

READ, KIRC, and LIHC are the cancer types where LMX1A-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Tertile	All	0.550	0.925	<.001	90	view →
KIRC	DFS	Tertile	IV	0.165	0.624	.004	54	view →
LIHC	OS	Tertile	II,III,IV	0.051	0.696	<.001	54	view →
KICH	DFS	Tertile	All	0.102	0.848	.004	39	view →
KIRP	DFS	Tertile	II,III,IV	0.191	0.781	<.001	36	view →
BLCA	OS	Tertile	All	0.097	0.688	<.001	36	view →
LAML	DFS	Tertile	All	0.232	0.584	.006	36	view →
CESC	DFS	Tertile	II,III,IV	0.184	0.705	.036	36	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
PAAD	DFS	Tertile	All	1.000	0.224	.008	33	view →
STAD	OS	Tertile	III,IV	0.195	0.531	.017	18	view →
UCEC	DFS	Tertile	All	0.820	0.899	.018	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

LMX1A-AS1–READ (OS)

Open the READ breakdown →