LMTK3

Across TCGA patient cohorts, LMTK3 mutation is significantly associated with the RNA expression of many other genes, with 1,402 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LMTK3-associated genes across cancer lineages are LINC02841, KCTD9, and OR6B2. Each is linked with LMTK3 in more than 2 cancer types. Because this analysis shows association rather than direction, both LMTK3-to-partner and partner-to-LMTK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02841 grouped by LMTK3-low versus LMTK3-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMTK3→partner) and Y-score (partner→LMTK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC02841 →	+0.032	+5.589	<.001	<.001	3	3
UCEC	KCTD9 →	+0.535	+2.343	.001	.003	3	3
CESC	OR6B2 →	+0.034	+2.824	.003	.009	3	2
READ	ZNF885P →	+0.101	+4.724	<.001	.003	3	2
READ	OR4B2P →	+0.047	+6.276	<.001	<.001	3	2
CESC	RN7SL847P →	+0.119	+3.273	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,402 associations by consensus.

LINC02841 by LMTK3 expression — CESC

Explore this box plot interactively →