LMOD3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LMOD3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,657 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LMOD3-associated genes across cancer lineages are DPP4, PPP1R27, and SMTNL2. Each is linked with LMOD3 in more than 2 cancer types. Because this analysis shows association rather than direction, both LMOD3-to-partner and partner-to-LMOD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LMOD3 versus DPP4 in UCEC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMOD3→partner) and Y-score (partner→LMOD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECDPP4 →+2.680+1.484<.001<.00133
HNSCPPP1R27 →+1.356+1.048<.001<.00132
HNSCSMTNL2 →+1.167+0.956<.001<.00132
UCECRCC2P4 →+0.827+1.018.005<.00132
HNSCMXD4 →+0.449+0.860.001<.00132
LSCCPGAP4 →-1.063-0.698.004.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,657 associations by consensus.

LMOD3 vs DPP4 — UCEC

Per-sample scatter of LMOD3 vs DPP4 in UCEC (Pearson r = 0.56).

Explore this scatter interactively →

Exploration