LMOD2

Across TCGA cell cohorts, LMOD2 mutation is significantly associated with the RNA expression of many other genes, with 143 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LMOD2-associated genes across cancer lineages are DTHD1, LIPN, and C4orf51. Each is linked with LMOD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LMOD2-to-partner and partner-to-LMOD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DTHD1 grouped by LMOD2-low versus LMOD2-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMOD2→partner) and Y-score (partner→LMOD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	DTHD1 →	+0.042	+4.087	<.001	.009	3	1
URINARY_TRACT	LIPN →	+0.112	+4.217	<.001	.005	3	1
LUNG_SCLC	C4orf51 →	+0.746	+5.643	<.001	.002	3	1
OVARY	ADAD1 →	+0.011	+3.807	<.001	.009	3	1
OVARY	LALBA →	+0.020	+3.405	<.001	.005	3	1
OVARY	PNLIP →	+0.019	+3.405	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 143 associations by consensus.

DTHD1 by LMOD2 expression — URINARY_TRACT

Explore this box plot interactively →