LMO7

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LMO7 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated LMO7 data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher LMO7 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated LMO7 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and COAD show a favorable association.

CCRCC, COAD, and UCEC are the cancer types where LMO7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCDFSTertileIII,IV0.8620.346<.00153view →
COADDFSMedianII,III,IV1.0000.884.02548view →
UCECDFSQuartileAll1.0000.843.01936view →
HNSCOSMedianIV0.8320.617.0155view →
LSCCOSQuartileAll0.9521.000.0314view →
PDACDFSTertileIV0.2170.777.0243view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

LMO7–CCRCC (DFS)

Kaplan–Meier survival curve for LMO7 mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration