LMO2

Across TCGA patient cohorts, LMO2 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LMO2-associated genes across cancer lineages are Memory B-cells, Epithelial cells, and naive B-cells. Each is linked with LMO2 in more than 2 cancer types. Because this analysis shows association rather than direction, both LMO2-to-partner and partner-to-LMO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Memory B-cells grouped by LMO2-low versus LMO2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMO2→partner) and Y-score (partner→LMO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Memory B-cells →	+0.031	+2.096	.011	.016	3	3
UCEC	Epithelial cells →	-0.086	-1.991	.007	.031	3	2
LUAD	naive B-cells →	+0.035	+5.217	<.001	.007	3	1
SKCM	Th2 cells →	+0.203	+3.465	.017	.003	3	1
UCEC	CD8+ naive T-cells →	+0.039	+2.202	.001	.033	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Memory B-cells by LMO2 expression — UCEC

Explore this box plot interactively →