LMO2

Across TCGA cell cohorts, LMO2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,311 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LMO2-associated GO terms across cancer lineages are Positive regulation of matrix metallopeptidase secretion, Postsynapse assembly, and Negative regulation of myoblast fusion. Each is linked with LMO2 in more than 6 cancer types. Because this analysis shows association rather than direction, both LMO2-to-partner and partner-to-LMO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of matrix metallopeptidase secretion grouped by LMO2-low versus LMO2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LMO2→partner) and Y-score (partner→LMO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Positive regulation of matrix metallopeptidase secretion →	-0.162	-2.005	<.001	.001	3	7
STOMACH	Postsynapse assembly →	-0.281	-1.122	<.001	.005	3	7
BREAST	Negative regulation of myoblast fusion →	+0.062	+0.899	.005	.002	3	7
SKIN	Positive regulation of myoblast differentiation →	+0.088	+0.855	<.001	.002	3	7
LARGE_INTESTINE	Regulation of viral genome replication →	+0.117	+0.928	.001	.004	3	6
LARGE_INTESTINE	Regulation of nucleocytoplasmic transport →	+0.042	+0.838	.004	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,311 associations by consensus.

Positive regulation of matrix metallopeptidase secretion by LMO2 expression — BLOOD_Lymphoma

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