LMO2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LMO2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,767 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible LMO2-associated genes across cancer lineages are CDH1, RPL6, and C8orf33. Each is linked with LMO2 in more than 4 cancer types. Because this analysis shows association rather than direction, both LMO2-to-partner and partner-to-LMO2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LMO2 versus CDH1 in LUNG_SCLC, with a Pearson correlation of -0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMO2→partner) and Y-score (partner→LMO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCCDH1 →-3.635-0.633<.001.00635
LUNG_SCLCRPL6 →+0.479+0.466<.001.00535
OESOPHAGUSC8orf33 →+0.881+0.636<.001.00235
BLOOD_MyelomaIRF7 →-1.880-0.697.008<.00135
UPPER_AERODIGESTIVE_TRACTLYPD3 →-2.237-0.704.001<.00135
SKINPFDN2 →+0.478+0.387.006.00535
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,767 associations by consensus.

LMO2 vs CDH1 — LUNG_SCLC

Per-sample scatter of LMO2 vs CDH1 in LUNG_SCLC (Pearson r = -0.52).

Explore this scatter interactively →

Exploration