Across TCGA patient cohorts, LMNTD2 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LMNTD2-associated genes across cancer lineages are 4E-BP1, Cyclin-B1, and eIF4E. Each is linked with LMNTD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LMNTD2-to-partner and partner-to-LMNTD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMNTD2→partner) and Y-score (partner→LMNTD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.336	+2.351	<.001	.003	3	2
UCEC	Cyclin-B1 →	+0.413	+2.321	.041	.033	3	2
UCEC	eIF4E →	+0.176	+3.183	.020	.009	3	1
UCEC	ERK2 →	+0.168	+2.415	.015	.003	3	1
UCEC	JNK2 →	+0.203	+2.009	.004	.017	3	1
UCEC	MEK1 →	+0.431	+2.807	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

LMNTD2 survival (RNA) · tumor vs normal (RNA) · all LMNTD2 data types