LMNTD1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LMNTD1 mutation is significantly associated with the RNA expression of many other genes, with 1,403 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LMNTD1-associated genes across cancer lineages are MIR378F, HSPE1-MOB4, and MIR369. Each is linked with LMNTD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both LMNTD1-to-partner and partner-to-LMNTD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR378F grouped by LMNTD1-low versus LMNTD1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMNTD1→partner) and Y-score (partner→LMNTD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAMIR378F →+0.337+7.640<.001.00933
UCECHSPE1-MOB4 →+0.141+1.892<.001<.00132
BLCAMIR369 →+0.365+7.640<.001.00932
SKCMRRM1-AS1 →+0.203+4.120.001<.00132
STADRNA5SP176 →+1.262+5.463<.001.00532
STADRNA5SP213 →+0.553+5.366<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,403 associations by consensus.

MIR378F by LMNTD1 expression — BLCA

Box plot of MIR378F in LMNTD1-low vs LMNTD1-high samples in BLCA.

Explore this box plot interactively →

Exploration