Across TCGA patient cohorts, LMLN mutation is significantly associated with the RNA expression of many other genes, with 2,310 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LMLN-associated genes across cancer lineages are RNA5SP176, RNU4-71P, and RN7SKP295. Each is linked with LMLN in more than 2 cancer types. Because this analysis shows association rather than direction, both LMLN-to-partner and partner-to-LMLN results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMLN→partner) and Y-score (partner→LMLN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP176 →	+0.215	+2.830	<.001	.007	3	3
BRCA	RNU4-71P →	+0.617	+6.711	<.001	<.001	3	3
SKCM	RN7SKP295 →	+0.177	+3.458	<.001	.004	3	3
UCEC	RPL23AP82 →	+0.303	+2.828	.001	.001	3	2
UCEC	CIDECP1 →	+0.441	+1.808	<.001	<.001	3	2
UCEC	ZNRF1 →	+0.368	+1.942	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,310 associations by consensus.

Exploration

LMLN survival (RNA) · tumor vs normal (RNA) · all LMLN data types