Across TCGA patient cohorts, LMLN mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LMLN-associated genes across cancer lineages are eEF2, EGFR_pY1068, and EGFR. Each is linked with LMLN in more than 1 cancer types. Because this analysis shows association rather than direction, both LMLN-to-partner and partner-to-LMLN results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMLN→partner) and Y-score (partner→LMLN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.265	+1.289	.020	.023	3	1
UCEC	EGFR_pY1068 →	-0.226	-2.058	.004	<.001	3	1
UCEC	EGFR →	-0.122	-2.222	.017	.010	3	1
UCEC	eIF4E →	+0.140	+1.777	.037	.002	3	1
UCEC	ERK2 →	+0.142	+1.765	.021	.013	3	1
UCEC	Fibronectin →	-0.309	-2.238	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration

LMLN survival (RNA) · tumor vs normal (RNA) · all LMLN data types