LMLN-AS1

Across TCGA pan-cancer cohorts, LMLN-AS1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated LMLN-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher LMLN-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LMLN-AS1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and CESC show a favorable association.

KIRC, STAD, and KICH are the cancer types where LMLN-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.760	0.845	<.001	94	view →
STAD	DFS	Median	IV	0.108	0.636	.001	52	view →
KICH	DFS	Quartile	All	0.552	0.958	.001	47	view →
PCPG	DFS	Tertile	All	0.579	0.797	.004	27	view →
SKCM	DFS	Tertile	II,III,IV	0.663	0.520	.017	23	view →
THCA	OS	Tertile	II,III,IV	0.888	0.969	.004	18	view →
CESC	OS	Median	All	0.863	0.757	.017	12	view →
READ	OS	Tertile	All	1.000	0.564	.010	12	view →
CHOL	OS	Tertile	II,III,IV	1.000	0.386	.026	11	view →
LUSC	OS	Median	III,IV	0.576	0.867	.027	6	view →
DLBC	DFS	Median	III,IV	1.000	0.146	.017	5	view →
ACC	DFS	Tertile	All	0.173	0.503	.033	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

LMLN-AS1–KIRC (DFS)

Open the KIRC breakdown →