LMF2

Across TCGA pan-cancer cohorts, LMF2 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated LMF2 data layer compared with 23 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher LMF2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated LMF2 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

CCRCC, HNSC, and PDAC are the cancer types where LMF2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	IV	0.188	0.961	.024	12	view →
HNSC	OS	Tertile	All	0.845	0.637	.013	10	view →
PDAC	DFS	Tertile	II,III,IV	0.224	0.467	.016	9	view →
LSCC	DFS	Tertile	II,III,IV	0.504	0.844	.028	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

LMF2–CCRCC (DFS)

Open the CCRCC breakdown →