LMF2

Across TCGA cell cohorts, LMF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,911 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LMF2-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cellular anatomical structure, Symbiont-mediated disruption of host anatomical structure, and Meiotic chromosome condensation. Each is linked with LMF2 in more than 14 cancer types. Because this analysis shows association rather than direction, both LMF2-to-partner and partner-to-LMF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cellular anatomical structure grouped by LMF2-low versus LMF2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LMF2→partner) and Y-score (partner→LMF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Symbiont-mediated disruption of host cellular anatomical structure →	+0.121	+0.664	<.001	.001	3	15
BREAST	Symbiont-mediated disruption of host anatomical structure →	+0.121	+0.664	<.001	.001	3	15
SKIN	Meiotic chromosome condensation →	+0.150	+1.428	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cilium assembly →	+0.086	+1.635	<.001	<.001	3	14
KIDNEY	Nuclear migration along microtubule →	+0.126	+0.762	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of calcium ion export across plasma membrane →	+0.076	+1.180	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,911 associations by consensus.

Symbiont-mediated disruption of host cellular anatomical structure by LMF2 expression — BREAST

Explore this box plot interactively →