LMF1

Across TCGA pan-cancer cohorts, LMF1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of LMF1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where LMF1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LMF1 is over-expressed in tumor, although a few such as UCEC and LUSC show the opposite, repressed pattern.

KIRP, COAD, and KIRC are the cancer types where LMF1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LMF1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	II,III,IV	+0.738	<.001	11	view →
COAD	All	III,IV	+0.663	<.001	10	view →
KIRC	Female	All	+0.388	<.001	9	view →
LIHC	Male	II,III,IV	+0.694	<.001	8	view →
UCEC	All	II,III,IV	−0.773	<.001	6	view →
LUSC	Female	All	−0.715	<.001	6	view →
BLCA	All	III,IV	−0.666	.001	6	view →
THCA	Male	III,IV	−0.615	<.001	6	view →
CHOL	All	All	+0.958	<.001	5	view →
KICH	All	All	+0.563	<.001	5	view →
HNSC	All	II,III,IV	−0.476	<.001	5	view →
LUAD	Male	All	−0.393	<.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

LMF1–KIRP

Open the KIRP breakdown →