LMCD1

Across TCGA pan-cancer cohorts, LMCD1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated LMCD1 data layer compared with 26 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher LMCD1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated LMCD1 expression acts as an unfavorable survival marker.

LSCC, COAD, and CCRCC are the cancer types where LMCD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Quartile	II,III,IV	0.491	0.853	.011	13	view →
COAD	DFS	Median	III,IV	0.826	1.000	.023	12	view →
CCRCC	DFS	Median	III,IV	0.145	0.774	.016	9	view →
PDAC	DFS	Median	IV	0.199	0.680	.004	9	view →
GBM	OS	Median	All	0.756	0.870	.022	2	view →
LUAD	DFS	Median	II,III,IV	0.721	0.937	.036	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

LMCD1–LSCC (DFS)

Open the LSCC breakdown →