LMBRD2

Across TCGA patient cohorts, LMBRD2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,401 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LMBRD2-associated genes across cancer lineages are MRPS30, NADK2, and DNAJC21. Each is linked with LMBRD2 in more than 4 cancer types. Because this analysis shows association rather than direction, both LMBRD2-to-partner and partner-to-LMBRD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LMBRD2 versus MRPS30 in HNSC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMBRD2→partner) and Y-score (partner→LMBRD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MRPS30 →	+0.890	+0.414	.001	<.001	3	5
HNSC	NADK2 →	+0.464	+0.278	<.001	<.001	3	5
HNSC	DNAJC21 →	+0.540	+0.271	<.001	<.001	3	5
BRCA	CALD1 →	-0.902	-0.464	<.001	.006	3	5
OV	TPM4 →	-0.735	-0.488	.003	.003	3	5
CCRCC	CCDC113 →	+0.646	+0.276	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,401 associations by consensus.

LMBRD2 vs MRPS30 — HNSC

Explore this scatter interactively →