LMAN2L

Across TCGA cell cohorts, LMAN2L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,885 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LMAN2L-associated GO terms across cancer lineages are Negative regulation of defense response to virus, Positive regulation of translational initiation, and Phospholipid biosynthetic process. Each is linked with LMAN2L in more than 14 cancer types. Because this analysis shows association rather than direction, both LMAN2L-to-partner and partner-to-LMAN2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of defense response to virus grouped by LMAN2L-low versus LMAN2L-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LMAN2L→partner) and Y-score (partner→LMAN2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of defense response to virus →	+0.112	+0.714	<.001	.001	3	15
OESOPHAGUS	Positive regulation of translational initiation →	+0.109	+0.839	.007	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Phospholipid biosynthetic process →	+0.049	+0.789	<.001	<.001	3	14
SOFT_TISSUE	Cell division →	+0.068	+0.684	<.001	.001	2	14
UPPER_AERODIGESTIVE_TRACT	Nucleus organization →	+0.066	+1.055	<.001	<.001	3	13
BREAST	Vacuolar transport →	+0.050	+0.753	.002	.004	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,885 associations by consensus.

Negative regulation of defense response to virus by LMAN2L expression — SOFT_TISSUE

Explore this box plot interactively →