LMAN2

Across TCGA cell cohorts, LMAN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,850 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LMAN2-associated GO terms across cancer lineages are Positive regulation of protein exit from endoplasmic reticulum, Glycolipid catabolic process, and Endoplasmic reticulum organization. Each is linked with LMAN2 in more than 13 cancer types. Because this analysis shows association rather than direction, both LMAN2-to-partner and partner-to-LMAN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein exit from endoplasmic reticulum grouped by LMAN2-low versus LMAN2-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LMAN2→partner) and Y-score (partner→LMAN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Positive regulation of protein exit from endoplasmic reticulum →	+0.159	+0.945	<.001	.009	3	14
BONE	Glycolipid catabolic process →	+0.184	+0.716	<.001	<.001	3	13
CNS	Endoplasmic reticulum organization →	+0.067	+0.716	<.001	<.001	3	12
BONE	Glycosphingolipid catabolic process →	+0.200	+0.668	<.001	<.001	3	11
BLOOD_Myeloma	Multi-pass transmembrane protein insertion into ER membrane →	+0.147	+1.020	.002	.001	3	11
OVARY	Attachment of GPI anchor to protein →	+0.176	+0.899	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,850 associations by consensus.

Positive regulation of protein exit from endoplasmic reticulum by LMAN2 expression — BLOOD_Myeloma

Explore this box plot interactively →