LMAN1

Across TCGA patient cohorts, LMAN1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,653 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LMAN1-associated genes across cancer lineages are EPB41L1, SEC11C, and DIDO1. Each is linked with LMAN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both LMAN1-to-partner and partner-to-LMAN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LMAN1 versus EPB41L1 in COAD, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMAN1→partner) and Y-score (partner→LMAN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	EPB41L1 →	-0.980	-0.459	<.001	<.001	3	7
HNSC	SEC11C →	+0.800	+0.325	<.001	.001	3	6
COAD	DIDO1 →	-0.550	-0.315	.004	.001	3	6
BRCA	CEP68 →	-0.554	-0.480	<.001	<.001	3	6
UCEC	STK32C →	-0.756	-0.496	.002	.002	3	5
BRCA	CDS2 →	-0.495	-0.422	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,653 associations by consensus.

LMAN1 vs EPB41L1 — COAD

Explore this scatter interactively →