LMAN1

Across TCGA patient cohorts, LMAN1 mutation is significantly associated with the RNA expression of many other genes, with 524 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LMAN1-associated genes across cancer lineages are LINC01432, RNU1-17P, and TRAJ24. Each is linked with LMAN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LMAN1-to-partner and partner-to-LMAN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01432 grouped by LMAN1-low versus LMAN1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMAN1→partner) and Y-score (partner→LMAN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC01432 →	+0.736	+4.539	<.001	.008	3	2
UCEC	RNU1-17P →	+0.176	+1.935	<.001	.006	3	2
UCEC	TRAJ24 →	+0.294	+1.518	.007	.009	3	2
UCEC	SNORD90 →	+0.208	+1.795	.001	.004	3	2
READ	RN7SL22P →	+0.238	+5.039	.005	.008	3	2
SKCM	RN7SL567P →	+0.116	+2.743	.004	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 524 associations by consensus.

LINC01432 by LMAN1 expression — CESC

Explore this box plot interactively →