LMAN1

Across TCGA cell cohorts, LMAN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,379 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LMAN1-associated GO terms across cancer lineages are Protein exit from endoplasmic reticulum, Positive regulation of protein exit from endoplasmic reticulum, and COPII-coated vesicle cargo loading. Each is linked with LMAN1 in more than 13 cancer types. Because this analysis shows association rather than direction, both LMAN1-to-partner and partner-to-LMAN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein exit from endoplasmic reticulum grouped by LMAN1-low versus LMAN1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LMAN1→partner) and Y-score (partner→LMAN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein exit from endoplasmic reticulum →	+0.172	+1.052	<.001	<.001	3	14
LIVER	Positive regulation of protein exit from endoplasmic reticulum →	+0.163	+1.125	<.001	<.001	3	13
LIVER	COPII-coated vesicle cargo loading →	+0.142	+0.765	.002	.005	3	13
BONE	Endoplasmic reticulum to cytosol transport →	+0.179	+1.152	<.001	<.001	3	12
BONE	Retrograde protein transport, ER to cytosol →	+0.179	+1.152	<.001	<.001	3	12
LIVER	Protein N-linked glycosylation →	+0.107	+1.224	.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,379 associations by consensus.

Protein exit from endoplasmic reticulum by LMAN1 expression — BONE

Explore this box plot interactively →