LLPHP2

Across TCGA patient cohorts, LLPHP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,556 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LLPHP2-associated GO terms across cancer lineages are Centrosome duplication, Protein acetylation, and Protein modification by small protein removal. Each is linked with LLPHP2 in more than 26 cancer types. Because this analysis shows association rather than direction, both LLPHP2-to-partner and partner-to-LLPHP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centrosome duplication grouped by LLPHP2-low versus LLPHP2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LLPHP2→partner) and Y-score (partner→LLPHP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Centrosome duplication →	+0.065	+0.205	<.001	<.001	3	27
ESCA	Protein acetylation →	+0.059	+0.193	.001	<.001	3	27
ESCA	Protein modification by small protein removal →	+0.069	+0.272	.001	<.001	3	27
ESCA	Regulation of RNA splicing →	+0.073	+0.236	<.001	<.001	3	27
ESCA	Regulation of telomere maintenance via telomere lengthening →	+0.070	+0.223	<.001	<.001	3	26
ESCA	Protein localization to microtubule organizing center →	+0.070	+0.224	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,556 associations by consensus.

Centrosome duplication by LLPHP2 expression — ESCA

Explore this box plot interactively →