LLGL2

Across TCGA pan-cancer cohorts, LLGL2 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated LLGL2 data layer compared with 24 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher LLGL2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated LLGL2 expression acts as an unfavorable survival marker, although some lineages such as COAD and CCRCC show a favorable association.

COAD, CCRCC, and UCEC are the cancer types where LLGL2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.887	.022	36	view →
CCRCC	OS	Quartile	All	0.966	0.681	.004	33	view →
UCEC	DFS	Tertile	II,III,IV	1.000	0.364	.003	28	view →
PDAC	DFS	Quartile	All	0.616	0.224	.003	12	view →
GBM	DFS	Quartile	All	0.455	0.246	.006	11	view →
LSCC	DFS	Tertile	II,III,IV	0.898	0.656	.023	7	view →
HNSC	OS	Median	IV	0.849	0.631	.023	2	view →
LUAD	DFS	Tertile	II,III,IV	0.323	0.627	.035	2	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

LLGL2–COAD (DFS)

Open the COAD breakdown →