LLGL2

Across TCGA patient cohorts, LLGL2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,232 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LLGL2-associated genes across cancer lineages are ADAM19, GFPT2, and BEND6. Each is linked with LLGL2 in more than 6 cancer types. Because this analysis shows association rather than direction, both LLGL2-to-partner and partner-to-LLGL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LLGL2 versus ADAM19 in OV, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LLGL2→partner) and Y-score (partner→LLGL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ADAM19 →	-0.927	-0.717	.006	.002	3	7
CCRCC	GFPT2 →	-1.438	-0.217	<.001	<.001	3	7
CCRCC	BEND6 →	-0.719	-0.341	<.001	<.001	3	7
CCRCC	CGN →	+1.271	+0.304	<.001	<.001	3	7
OV	IFFO1 →	-0.707	-0.595	.001	<.001	3	6
HNSC	MISP3 →	+0.837	+0.469	.003	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,232 associations by consensus.

LLGL2 vs ADAM19 — OV

Explore this scatter interactively →