LLGL2

Across TCGA cell cohorts, LLGL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,212 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible LLGL2-associated GO terms across cancer lineages are Establishment of epithelial cell apical/basal polarity, Negative regulation of Arp2/3 complex-mediated actin nucleation, and Bundle of His cell to Purkinje myocyte communication. Each is linked with LLGL2 in more than 15 cancer types. Because this analysis shows association rather than direction, both LLGL2-to-partner and partner-to-LLGL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of epithelial cell apical/basal polarity grouped by LLGL2-low versus LLGL2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LLGL2→partner) and Y-score (partner→LLGL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Establishment of epithelial cell apical/basal polarity →	-0.233	-2.232	<.001	<.001	3	16
KIDNEY	Negative regulation of Arp2/3 complex-mediated actin nucleation →	+0.218	+2.162	.004	<.001	3	15
SOFT_TISSUE	Bundle of His cell to Purkinje myocyte communication →	+1.021	+1.980	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Sensory perception of salty taste →	+1.726	+1.944	<.001	.001	3	13
PANCREAS	Response to indole-3-methanol →	+0.233	+1.963	<.001	<.001	3	12
PANCREAS	Cellular response to indole-3-methanol →	+0.234	+1.804	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,212 associations by consensus.

Establishment of epithelial cell apical/basal polarity by LLGL2 expression — URINARY_TRACT

Explore this box plot interactively →