LIVAR

Across TCGA patient cohorts, LIVAR RNA expression is significantly associated with the protein abundance of many other proteins, with 7,940 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible LIVAR-associated proteins across cancer lineages are ARHGEF1_S631, PXN_S533, and SEC63_T537. Each is linked with LIVAR in more than 3 cancer types. Because this analysis shows association rather than direction, both LIVAR-to-partner and partner-to-LIVAR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LIVAR versus ARHGEF1_S631 in CCRCC, with a Pearson correlation of -0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LIVAR→partner) and Y-score (partner→LIVAR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ARHGEF1_S631 →	-0.743	-0.884	<.001	<.001	3	4
CCRCC	PXN_S533 →	-0.739	-0.580	.006	.006	3	4
CCRCC	SEC63_T537 →	-0.795	-0.770	<.001	<.001	3	4
HNSC	SLK_S518 →	-0.934	-0.803	.004	.009	3	4
CCRCC	PHRF1_S814 →	-0.513	-0.713	<.001	<.001	3	4
LSCC	STAT2_S595 →	-0.650	-0.427	.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,940 associations by consensus.

LIVAR vs ARHGEF1_S631 — CCRCC

Explore this scatter interactively →