Across TCGA patient cohorts, LITAF protein abundance is significantly associated with the RNA expression of many other genes, with 12,743 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LITAF-associated genes across cancer lineages are AQP9, PLEK, and CSF3R. Each is linked with LITAF in more than 4 cancer types. Because this analysis shows association rather than direction, both LITAF-to-partner and partner-to-LITAF results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LITAF→partner) and Y-score (partner→LITAF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	AQP9 →	+3.224	+1.069	<.001	<.001	3	5
GBM	PLEK →	+1.497	+0.772	<.001	.001	3	5
GBM	CSF3R →	+1.807	+0.998	<.001	<.001	3	5
GBM	BCL2A1 →	+2.580	+0.825	<.001	<.001	3	5
GBM	ITGAX →	+1.372	+1.003	.001	<.001	3	5
PDAC	FCGR3B →	+1.485	+0.651	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,743 associations by consensus.

Exploration

LITAF survival (RNA) · tumor vs normal (RNA) · all LITAF data types