Across TCGA patient cohorts, LITAF mutation is significantly associated with the RNA expression of many other genes, with 556 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LITAF-associated genes across cancer lineages are RN7SL346P, RNU6-861P, and CDY7P. Each is linked with LITAF in more than 2 cancer types. Because this analysis shows association rather than direction, both LITAF-to-partner and partner-to-LITAF results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LITAF→partner) and Y-score (partner→LITAF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL346P →	+0.175	+2.759	<.001	.002	3	3
SKCM	RNU6-861P →	+0.536	+7.219	<.001	<.001	3	2
SKCM	CDY7P →	+0.044	+5.292	<.001	.006	3	2
SKCM	MIR3115 →	+0.915	+5.680	<.001	.003	3	1
UCEC	TAF9 →	+0.546	+3.191	.002	.009	3	1
UCEC	PANO1 →	+0.771	+3.724	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 556 associations by consensus.

Exploration

LITAF survival (RNA) · tumor vs normal (RNA) · all LITAF data types