Across TCGA cell cohorts, LITAF RNA expression is significantly associated with the go_rna of many other GO terms, with 3,732 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LITAF-associated GO terms across cancer lineages are Negative regulation of actin filament polymerization, Positive regulation of canonical NF-kappaB signal transduction, and Membrane raft organization. Each is linked with LITAF in more than 11 cancer types. Because this analysis shows association rather than direction, both LITAF-to-partner and partner-to-LITAF results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LITAF→partner) and Y-score (partner→LITAF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of actin filament polymerization →	+0.127	+1.621	<.001	<.001	2	12
PANCREAS	Positive regulation of canonical NF-kappaB signal transduction →	+0.068	+1.493	<.001	<.001	3	11
OESOPHAGUS	Membrane raft organization →	+0.158	+1.020	<.001	.002	3	11
OESOPHAGUS	Regulation of protein localization to plasma membrane →	+0.085	+1.059	.001	.001	3	10
PANCREAS	Modulation by symbiont of entry into host →	+0.173	+1.351	<.001	<.001	3	10
PANCREAS	Plasma membrane organization →	+0.093	+1.283	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,732 associations by consensus.

Exploration

LITAF survival (RNA) · tumor vs normal (RNA) · all LITAF data types