LIPT2

Across TCGA patient cohorts, LIPT2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,283 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LIPT2-associated genes across cancer lineages are ZNF480, MXRA5Y, and RND3. Each is linked with LIPT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LIPT2-to-partner and partner-to-LIPT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LIPT2 versus ZNF480 in OV, with a Pearson correlation of -0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIPT2→partner) and Y-score (partner→LIPT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZNF480 →	-0.561	-0.401	<.001	.003	3	2
BRCA	MXRA5Y →	-0.502	-0.342	.001	.003	3	2
BRCA	RND3 →	-0.809	-0.454	.003	.002	3	2
BRCA	P4HA1 →	-0.879	-0.544	<.001	.001	3	2
BRCA	NT5DC2 →	-0.897	-0.507	.002	.001	3	2
BRCA	LINC00888 →	-0.850	-0.560	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,283 associations by consensus.

LIPT2 vs ZNF480 — OV

Explore this scatter interactively →