LIPT1

Across TCGA patient cohorts, LIPT1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,782 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LIPT1-associated genes across cancer lineages are TMEM164, ARID3A, and DDX39A. Each is linked with LIPT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both LIPT1-to-partner and partner-to-LIPT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LIPT1 versus TMEM164 in HNSC, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIPT1→partner) and Y-score (partner→LIPT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TMEM164 →	+0.493	+0.463	<.001	.006	3	2
LUAD	ARID3A →	-0.722	-0.654	.009	.003	3	2
GBM	DDX39A →	-0.859	-0.485	<.001	.002	3	2
BRCA	PLCB3 →	-1.056	-0.490	<.001	.001	3	2
BRCA	POLD1 →	-1.136	-0.510	.008	.002	2	3
BRCA	CD276 →	-0.830	-0.536	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,782 associations by consensus.

LIPT1 vs TMEM164 — HNSC

Explore this scatter interactively →