LIPT1

Across TCGA cell cohorts, LIPT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,497 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LIPT1-associated GO terms across cancer lineages are Peptidyl-lysine modification, Negative regulation of hematopoietic stem cell differentiation, and Regulation of natural killer cell mediated immune response to tumor cell. Each is linked with LIPT1 in more than 10 cancer types. Because this analysis shows association rather than direction, both LIPT1-to-partner and partner-to-LIPT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine modification grouped by LIPT1-low versus LIPT1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LIPT1→partner) and Y-score (partner→LIPT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Peptidyl-lysine modification →	+0.052	+0.891	.002	<.001	3	11
OVARY	Negative regulation of hematopoietic stem cell differentiation →	+0.143	+0.666	<.001	.001	3	10
STOMACH	Regulation of natural killer cell mediated immune response to tumor cell →	-0.288	-0.800	.001	<.001	3	10
KIDNEY	Positive regulation of vasculature development →	-0.099	-0.504	.006	.004	3	9
SOFT_TISSUE	Mitochondrial tRNA modification →	+0.079	+0.445	.008	.002	3	8
PANCREAS	Establishment of protein localization to vacuole →	+0.054	+0.518	.005	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,497 associations by consensus.

Peptidyl-lysine modification by LIPT1 expression — OESOPHAGUS

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