Across TCGA cell cohorts, LIPN RNA expression is significantly associated with the RNA expression of many other genes, with 778 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LIPN-associated genes across cancer lineages are SERPINB10, SIGLEC14, and LIPK. Each is linked with LIPN in more than 2 cancer types. Because this analysis shows association rather than direction, both LIPN-to-partner and partner-to-LIPN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIPN→partner) and Y-score (partner→LIPN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SERPINB10 →	+1.505	+0.216	<.001	.005	3	3
BLOOD_Leukemia	SIGLEC14 →	+1.039	+0.214	<.001	.005	3	2
OESOPHAGUS	LIPK →	+0.610	+0.060	<.001	.001	2	3
OVARY	CXorf51A →	+0.155	+0.021	<.001	<.001	3	2
LUNG_NSCLC_LUAD	IRGM →	+0.300	+0.012	.001	.004	3	2
URINARY_TRACT	DPRX →	+0.100	+0.114	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 778 associations by consensus.

Exploration

LIPN survival (RNA) · tumor vs normal (RNA) · all LIPN data types