Across TCGA cell cohorts, LIPN RNA expression is significantly associated with the go_rna of many other GO terms, with 240 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LIPN-associated GO terms across cancer lineages are Synaptic vesicle maturation, Protein polyglutamylation, and Negative regulation of interleukin-1 alpha production. Each is linked with LIPN in more than 2 cancer types. Because this analysis shows association rather than direction, both LIPN-to-partner and partner-to-LIPN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LIPN→partner) and Y-score (partner→LIPN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Synaptic vesicle maturation →	+0.070	+0.216	<.001	.005	3	2
BLOOD_Leukemia	Protein polyglutamylation →	-0.051	-0.238	<.001	.008	2	3
BLOOD_Leukemia	Negative regulation of interleukin-1 alpha production →	+0.746	+0.160	.001	.008	3	2
BLOOD_Leukemia	Retrograde transport, endosome to Golgi →	+0.033	+0.220	.001	.008	3	2
BLOOD_Leukemia	Positive regulation of CD4-positive, alpha-beta T cell differentiation →	+0.079	+0.252	<.001	.008	3	2
BLOOD_Leukemia	Nitric oxide metabolic process →	-0.067	-0.305	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 240 associations by consensus.

Exploration

LIPN survival (RNA) · tumor vs normal (RNA) · all LIPN data types