Across TCGA cell cohorts, LIPK mutation is significantly associated with the mutation status of many other genes, with 525 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LIPK-associated genes across cancer lineages are CCDC175, NKAP, and HIF3A. Each is linked with LIPK in more than 2 cancer types. Because this analysis shows association rather than direction, both LIPK-to-partner and partner-to-LIPK results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIPK→partner) and Y-score (partner→LIPK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	CCDC175 →	+5.415	+5.415	.004	.004	1	3
BLOOD_Lymphoma	NKAP →	+6.014	+6.014	.001	.001	1	3
BLOOD_Lymphoma	HIF3A →	+4.429	+5.247	.005	.005	1	3
OVARY	BRD2 →	+5.415	+5.415	.004	.004	1	2
BLOOD_Lymphoma	SF3A1 →	+5.014	+5.584	.003	.003	1	2
OVARY	CMIP →	+4.415	+4.977	.007	.007	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 525 associations by consensus.

Exploration

LIPK survival (RNA) · tumor vs normal (RNA) · all LIPK data types