Across TCGA patient cohorts, LIPI RNA expression is significantly associated with the protein abundance of many other proteins, with 11,646 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LIPI-associated proteins across cancer lineages are NELFE, POGZ, and POLR2B. Each is linked with LIPI in more than 4 cancer types. Because this analysis shows association rather than direction, both LIPI-to-partner and partner-to-LIPI results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LIPI→partner) and Y-score (partner→LIPI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NELFE →	+0.627	+0.283	<.001	.005	3	5
GBM	POGZ →	+0.276	+0.482	<.001	<.001	3	4
LSCC	POLR2B →	+0.170	+0.384	<.001	.001	3	4
GBM	RBM10 →	+0.354	+0.594	<.001	<.001	3	4
GBM	ZMYM4 →	+0.258	+0.431	.001	.001	3	4
GBM	RXRB →	+0.287	+0.376	.004	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,646 associations by consensus.

Exploration

LIPI survival (RNA) · tumor vs normal (RNA) · all LIPI data types