LIPG

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LIPG protein abundance is significantly associated with the RNA expression of many other genes, with 7,064 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LIPG-associated genes across cancer lineages are CCDC115, DNAJB12, and PLOD2. Each is linked with LIPG in more than 2 cancer types. Because this analysis shows association rather than direction, both LIPG-to-partner and partner-to-LIPG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LIPG versus CCDC115 in UCEC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIPG→partner) and Y-score (partner→LIPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCCDC115 →-0.535-0.615.004.00233
UCECDNAJB12 →-0.491-0.674.001<.00133
GBMPLOD2 →+1.261+0.612<.001<.00133
LUADMCRIP2 →-0.744-0.762.001.00133
UCECFIS1 →-1.812-0.971<.001.00133
UCECHNRNPA3P5 →+1.509+0.875.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,064 associations by consensus.

LIPG vs CCDC115 — UCEC

Per-sample scatter of LIPG vs CCDC115 in UCEC (Pearson r = -0.37).

Explore this scatter interactively →

Exploration