LIPF

Across TCGA patient cohorts, LIPF mutation is significantly associated with the RNA expression of many other genes, with 2,493 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LIPF-associated genes across cancer lineages are LINC02438, EIF1, and GAS2L1. Each is linked with LIPF in more than 2 cancer types. Because this analysis shows association rather than direction, both LIPF-to-partner and partner-to-LIPF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02438 grouped by LIPF-low versus LIPF-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIPF→partner) and Y-score (partner→LIPF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC02438 →	+0.705	+4.061	.004	.001	3	3
SKCM	EIF1 →	+0.325	+2.632	.006	.005	3	2
SKCM	GAS2L1 →	+0.619	+3.813	.003	<.001	3	2
SKCM	MIR103A1 →	+0.136	+3.080	<.001	.006	3	2
SKCM	GNL1 →	+0.418	+2.745	.008	.003	3	2
SKCM	CLIC1 →	+0.597	+3.497	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,493 associations by consensus.

LINC02438 by LIPF expression — LUAD

Explore this box plot interactively →