LINS1

Across TCGA cell cohorts, LINS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,452 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LINS1-associated GO terms across cancer lineages are Mitotic G2/M transition checkpoint, Cell cycle checkpoint signaling, and DNA damage checkpoint signaling. Each is linked with LINS1 in more than 14 cancer types. Because this analysis shows association rather than direction, both LINS1-to-partner and partner-to-LINS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic G2/M transition checkpoint grouped by LINS1-low versus LINS1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINS1→partner) and Y-score (partner→LINS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Mitotic G2/M transition checkpoint →	+0.111	+1.125	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cell cycle checkpoint signaling →	+0.087	+1.169	.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	DNA damage checkpoint signaling →	+0.087	+1.291	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of G2/M transition of mitotic cell cycle →	+0.090	+0.999	.001	.006	3	14
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication maintenance of fidelity →	+0.109	+1.052	<.001	.002	3	14
UPPER_AERODIGESTIVE_TRACT	DNA recombination →	+0.078	+1.178	.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,452 associations by consensus.

Mitotic G2/M transition checkpoint by LINS1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →