Across TCGA patient cohorts, LINGO4 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,919 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LINGO4-associated proteins across cancer lineages are RASIP1_S41, SELENBP1, and RABL6. Each is linked with LINGO4 in more than 4 cancer types. Because this analysis shows association rather than direction, both LINGO4-to-partner and partner-to-LINGO4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LINGO4→partner) and Y-score (partner→LINGO4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	RASIP1_S41 →	+0.584	+0.416	.001	.002	3	5
UCEC	SELENBP1 →	+0.782	+0.718	<.001	<.001	3	5
BRCA	RABL6 →	+0.198	+0.266	.001	.005	3	4
LSCC	REEP4_S152 →	-0.456	-0.108	<.001	.006	3	4
HNSC	TSTD1 →	+0.362	+0.246	<.001	.009	3	4
CCRCC	ZBTB20 →	+0.304	+0.307	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,919 associations by consensus.

Exploration

LINGO4 survival (RNA) · tumor vs normal (RNA) · all LINGO4 data types